Publications
All publications
Single-cell transcriptomic landscape of the developing human spinal cord. Andersen J*, Thom N*, Shadrach JL, Chen X, Onesto MM, Amin ND, Yoon SJ, Li L, Greenleaf WJ, Müller F, Pașca A, Kaltschmidt JA, Pașca SP. Nature Neuroscience, 2023. PDF Main and Suppl
Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway. Kim JI, Miura Y, Li MY, Revah O, Selvaraj S, Birey F, Meng X, Thete MV, Pavlov SD, Andersen J, Pașca AM, Porteus MH, Huguenard JR, Pașca SP. bioRxiv, 2023. doi: https://doi.org/10.1101/2023.03.15.530726
Maturation and circuit integration of transplanted human cortical organoids. Revah O, Gore F, Kelley KW, Andersen J, Sakai N, Chen X, Li ML, Birey F, Yang X, Saw NL, Baker SW, Amin ND, Kulkarni S, Mudipalli R, Cui B, Nishino S, Grant GA, Knowles JK, Shamloo M, Huguenard JR, Deisseroth K & Pașca SP. Nature, 610, 319–326, 2022.
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution. Trevino AE*, Müller F*, Andersen J*, Sundaram L*, Kathiria A, Shcherbina A, Farh K, Chang HY, Paşca AM, Kundaje A, Paşca SP, Greenleaf WJ. Cell, 184, 5053-5069, 2021. PDF main
Long term maturation of cortical organoids matches key early postnatal transitions. Gordon A, Yoon SJ, Tran SS, Makinson CD, Park JY, Andersen J, Valencia AM, Horvath S, Xiaou X, Huguenard JR, Paşca SP, Geschwind DH. Nature Neuroscience, 24, 331-342, 2021. PDF
Generation of functional human 3D cortico-motor assembloids. Andersen J, Revah O, Miura Y, Thom N, Amin ND, Kelley KW, Singh M, Chen X, Thete MV, Walczak EM, Vogel H, Fan C & Paşca SP. Cell 183, 1913-1929, 2020. PDF Main Suppl
Chromatin accessibility dynamics in a model of human forebrain development. Trevino AE*, Sinnott-Armstrong N*, Andersen J*, Yoon SJ, Huber N, Pritchard JK, Chang HY, Greenleaf WJ & Paşca SP. Science 367 (4476), 2020. PDF
Absent forebrain replaced by embryonic stem cells. Andersen J & Paşca SP. Nature 563 (7729), 44-45, 2018.
Generation and assembly of human brain region-specific 3D cultures. Sloan SA*, Andersen J*, Paşca AM*, Birey F* & Paşca SP. Nature Protocols 13(9):2062-2085, 2018. PDF
Assembly of functionally integrated human forebrain spheroids. Birey F*, Andersen J*, Makinson CD*, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O’Rourke NA, Steinmetz LM, Bernstein JA, Hallmayer J, Huguenard JR & Pașca SP. Nature 545(7652): 54-59, 2017. PDF
Return to quiescence of mouse neural stem cells by degradation of a proactivation protein. Urbán N, van den Berg D, Forget A, Andersen J, Demmers JA, Hunt C, Ayrault O & Guillemot F. Science 353(6296): 292-295, 2016. PDF
NFIX regulates proliferation and migration within the murine SVZ neurogenic niche. Heng YH, Zhou B, Harris L, Smith A, Horne B, Martynoga B, Andersen J, Achimastou A, Cato K, Richards J, Gronostajski RM, Yeo GS, Guillemot F, Bailey TL & Piper M. Cerebral Cortex 25(10): 3758-3778, 2014. PDF
A transcriptional mechanism integrating inputs from extracellular signals to activate hippocampal stem cells. Andersen J, Urbán N, Achimastou A, Ito A, Simic M, Ullom K, Martynoga B, Lebel M, Göritz C, Frisén J, Nakafuku M & Guillemot F. Neuron 83(5): 1085-97, 2014. PDF
Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence. Martynoga B, Mateo JL, Zhou B, Andersen J, Achimastou A, Urbán N, van den Berg D, Georgopoulou D, Hadjur S, Wittbrodt J, Ettwiller J, Piper M, Gronostajski RM & Guillemot F. Genes & Development 27(16): 1769-86, 2013. PDF
The Nicotinic Acetylcholine Receptor Partial Agonist Varenicline Increases the Ataxic and Sedative-Hypnotic Effects of Acute Ethanol Administration in C57BL/6J Mice. Kamens HM, Andersen J & Picciotto MR. Alcoholism, clinical and experimental research 34(12): 2053-60, 2010.
Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice. Kamens HM, Andersen J & Picciotto MR. Psychopharmacology (Berl) 208(4): 613-26, 2010.